CD81 anticorps

N° du produit ABIN4949542

L’anticorps Souris Monoclonal anti-CD81 a été validé pour FACS, WB, IF, Func et IHC (p). Il convient pour détecter CD81 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CD81 anticorps (ABIN4949542)

Antigène: CD81

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD81 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1-3-3-22

Détail du produit anti-CD81 anticorps

Purification: Protein G affinity chromatography

Immunogène: A B-cell line derived from a Burkitt lymphoma was used as the immunogen for the CD81 antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal dilution of the CD81 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,WB: 0.5-1 μg/mL,Functional Studies: order BSA free formulation,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CD81 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur CD81

Antigène: CD81

Autre désignation: CD81

Sujet: This mAb recognizes a protein of 26  kDa, identified as CD81 (Workshop VI, Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

Pathways: Inositol Metabolic Process, Hepatitis C