CD81 anticorps (full length)
Aperçu rapide pour CD81 anticorps (full length) (ABIN4949542)
Antigène
Voir toutes CD81 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- full length
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Fonction
- CD81 Antibody (azide and preservative free)
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Purification
- Protein G affinity chromatography
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Immunogène
- Recombinant full length human protein was used as the immunogen for the CD81 antibody.
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal dilution of the CD81 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the CD81 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CD81
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Autre désignation
- CD81
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Sujet
- This mAb recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.
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UniProt
- P60033
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Pathways
- Inositol Metabolic Process, Hepatitis C
Antigène
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