Filaggrin anticorps (AA 998-1104)

N° du produit ABIN4949675

Cet anticorps anti-Filaggrin est un anticorps Souris Monoclonal détectant Filaggrin dans IF, FACS et IHC (p). Adapté pour Humain.

Aperçu rapide pour Filaggrin anticorps (AA 998-1104) (ABIN4949675)

Antigène: Filaggrin (FLG)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Filaggrin est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FLG-1561

Détail du produit anti-Filaggrin anticorps

Épitope: AA 998-1104

Purification: Protein G affinity chromatography

Immunogène: Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Filaggrin antibody should be determined by the researcher.\. FACS: 0.5-1 μg/10^6 cells in 0.1ml,IF: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Filaggrin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur Filaggrin

Antigène: Filaggrin (FLG)

Autre désignation: Filaggrin

Sujet: Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.

Pathways: Sensory Perception of Sound, Stem Cell Maintenance