LGALS1/Galectin 1 anticorps (AA 12-108)

N° du produit ABIN4949704

L’anticorps Souris Monoclonal anti-LGALS1/Galectin 1 a été validé pour WB, ELISA, FACS, IF et IHC (p). Il convient pour détecter LGALS1/Galectin 1 dans des échantillons de Humain.

Aperçu rapide pour LGALS1/Galectin 1 anticorps (AA 12-108) (ABIN4949704)

Antigène: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LGALS1/Galectin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GAL1-1831

Détail du produit anti-LGALS1/Galectin 1 anticorps

Épitope: AA 12-108

Purification: Protein G affinity chromatography

Immunogène: A human partial recombinant protein corresponding to amino acids 12-108 was used as the immunogen for the Galectin 1 antibody.

Isotype: IgG1 lambda

Information d'application

Indications d'application: Titering of the Galectin 1 antibody may be required for optimal performance.\. ELISA: 2-4 μg/mL, order the BSA-free formulation for coating,IF: 1-2 μg/mL,Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,WB: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Galectin 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur LGALS1/Galectin 1

Antigène: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Autre désignation: Galectin 1

Sujet: Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.

Pathways: Carbohydrate Homeostasis