GP2 anticorps (AA 35-179)

N° du produit ABIN4949728

L’anticorps anti-GP2 Monoclonal Souris est utilisé pour la détection de GP2 dans des échantillons de Humain. Il a été validé pour FACS, IF et IHC (p).

Aperçu rapide pour GP2 anticorps (AA 35-179) (ABIN4949728)

Antigène: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GP2 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GP2-1712

Détail du produit anti-GP2 anticorps

Épitope: AA 35-179

Aucune reactivité croisée: Souris

Purification: Protein G affinity chromatography

Immunogène: A partial human recombinant protein corresponding to amino acids 35-179 was used as the immunogen for the GP2 antibody.

Isotype: IgG2b lambda

Information d'application

Indications d'application: Optimal dilution of the GP2 antibody should be determined by the researcher.\. FACS: 0.5-1 μg/10e6 cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the GP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur GP2

Antigène: GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))

Autre désignation: Glycoprotein 2 / GP2 / ZAP75

Sujet: GP2 (Glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.