Plakophilin 1 anticorps (N-Term)

N° du produit ABIN4949852

Cet anticorps anti-Plakophilin 1 Monoclonal Souris (Clone 10B2) (ABIN4949852) détecte spécifiquement Plakophilin 1 dans WB et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Plakophilin 1 anticorps (N-Term) (ABIN4949852)

Antigène: Plakophilin 1 (PKP1)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Plakophilin 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 10B2

Détail du produit anti-Plakophilin 1 anticorps

Épitope: AA 1-27, N-Term

Purification: Protein G affinity chromatography

Immunogène: A N-terminal human recombinant protein fragment was used as the immunogen for the Plakophilin 1 antibody. Its epitope maps to between amino acids 1-27 of human PKP1.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal dilution of the Plakophilin 1 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IF: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Plakophilin 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur Plakophilin 1

Antigène: Plakophilin 1 (PKP1)

Autre désignation: Plakophilin 1

Sujet: Recognizes a protein of 75  kDa, identified as Plakophilin 1 (PKP1). Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. PKP1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). PKP2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.