TIMP2 anticorps (AA 56-66)

N° du produit ABIN4949915

Cet anticorps anti-TIMP2 est un anticorps Souris Monoclonal détectant TIMP2 dans WB, IF et IHC (p). Adapté pour Humain, Rat, Souris, Boeuf (Vache), Poisson zèbre (Danio rerio), Lapin et Cobaye.

Aperçu rapide pour TIMP2 anticorps (AA 56-66) (ABIN4949915)

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Poisson zèbre (Danio rerio), Lapin, Cobaye

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TIMP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3A4

Détail du produit anti-TIMP2 anticorps

Épitope: AA 56-66

Purification: Protein G affinity chromatography

Immunogène: Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this TIMP-2 antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TIMP-2 antibody to be titered up or down for optimal performance.\. IHC (FFPE): 0.5-1 μg/mL for 30 min at RT,WB: 0.5-1 μg/mL,IF: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the TIMP-2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur TIMP2

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Autre désignation: TIMP2

Sujet: It recognizes a protein of 21  kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72  kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92  kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Pathways: cAMP Metabolic Process