TIMP2 anticorps (AA 56-66)

N° du produit ABIN4949916

Cet anticorps Souris Monoclonal détecte spécifiquement TIMP2 dans WB, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio) et Cobaye.

Aperçu rapide pour TIMP2 anticorps (AA 56-66) (ABIN4949916)

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio), Cobaye

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TIMP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3A4

Détail du produit anti-TIMP2 anticorps

Épitope: AA 56-66

Purification: Protein G affinity chromatography

Immunogène: Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this TIMP-2 antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TIMP-2 antibody to be titered up or down for optimal performance.\. IHC (FFPE): 0.5-1 μg/mL for 30 min at RT,WB: 0.5-1 μg/mL,IF: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the TIMP-2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur TIMP2

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Autre désignation: TIMP2

Sujet: It recognizes a protein of 21  kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72  kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92  kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Pathways: cAMP Metabolic Process