TIMP2 anticorps (N-Term)

N° du produit ABIN4949918

Cet anticorps anti-TIMP2 Monoclonal Souris (Clone SPM356) (ABIN4949918) détecte spécifiquement TIMP2 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TIMP2 anticorps (N-Term) (ABIN4949918)

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TIMP2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: SPM356

Détail du produit anti-TIMP2 anticorps

Épitope: N-Term

Fonction: TIMP2 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TIMP2 antibody to be titered up or down for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the TIMP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur TIMP2

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Autre désignation: TIMP2

Sujet: It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

UniProt: P16035

Pathways: cAMP Metabolic Process