Villin 1 anticorps (AA 179-311)

N° du produit ABIN4949934

Cet anticorps Souris Monoclonal détecte spécifiquement Villin 1 dans WB, IF, FACS et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Villin 1 anticorps (AA 179-311) (ABIN4949934)

Antigène: Villin 1 (VIL1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Villin 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: VIL1-1314

Détail du produit anti-Villin 1 anticorps

Épitope: AA 179-311

Purification: Protein G affinity chromatography

Immunogène: Amino acids 179-311 from the human protein were used as the immunogen for this Villin antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Titration of the Villin antibody may be required for optimal performance.\. FACS: 0.5-1 μg/10^6 cells in 0.1ml,IF: 1-2 μg/mL,Western blot: 1-2 μg/mL,IHC (FFPE): 0.25-0.5 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Villin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur Villin 1

Antigène: Villin 1 (VIL1)

Autre désignation: Villin

Sujet: Recognizes a protein of ~93  kDa which is identified as Villin (VIL1). It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, Villin is predominantly expressed in tumors of colorectal origin. Antibody to Villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization