Villin 1 anticorps (AA 179-311)
Aperçu rapide pour Villin 1 anticorps (AA 179-311) (ABIN4949934)
Antigène
Voir toutes Villin 1 (VIL1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Épitope
- AA 179-311
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Fonction
- Villin Antibody / VIL1 (azide and preservative free)
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Purification
- Protein G affinity chromatography
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Immunogène
- Amino acids 179-311 from the human protein were used as the immunogen for this Villin antibody.
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Isotype
- IgG1, kappa
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Indications d'application
- Titration of the Villin antibody may be required for optimal performance.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the Villin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Villin 1 (VIL1)
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Autre désignation
- Villin
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Sujet
- Recognizes a protein of ~93 kDa which is identified as Villin (VIL1). It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, Villin is predominantly expressed in tumors of colorectal origin. Antibody to Villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.
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UniProt
- P09327
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Pathways
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
Antigène
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