Arylsulfatase A anticorps

N° du produit ABIN4950226

L’anticorps anti-Arylsulfatase A Polyclonal produit chez le Lapin a été validé pour WB, IHC (p) et FACS. Il convient pour la détection de Arylsulfatase A dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour Arylsulfatase A anticorps (ABIN4950226)

Antigène: Arylsulfatase A (ARSA)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Arylsulfatase A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-Arylsulfatase A anticorps

Purification: Antigen affinity

Immunogène: Amino acids QALKQLQLLKAQLDAAVTFGPSQVARGED of human ARSA were used as the immunogen for the ARSA antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the ARSA antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the ARSA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Arylsulfatase A

Antigène: Arylsulfatase A (ARSA)

Autre désignation: ARSA

Sujet: Arylsulfatase A (ARSA) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate intocerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. ARSA is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

UniProt: P15289