Ceruloplasmin anticorps (AA 20-258)

N° du produit ABIN4950633

Détail du produit anti-Ceruloplasmin anticorps

Antigène: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Épitope: AA 20-258

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ceruloplasmin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Amino acids 20-258 of mouse Ceruloplasmin were used as the immunogen for the CP antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CP antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Ceruloplasmin

Antigène: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Autre désignation: Ceruloplasmin / CP (CP Produits)

Synonymes: anticorps CP-2, anticorps fi23f10, anticorps wu:fi23f10, anticorps D3Ertd555e, anticorps CERP, anticorps CP, anticorps ceruloplasmin, anticorps CP, anticorps cp, anticorps Cp, anticorps LOC100533122

Sujet: Ceruloplasmin (or Caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. It is mapped to 3q23-q25. The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

UniProt: Q61147

Pathways: Transition Metal Ion Homeostasis