Ceruloplasmin anticorps (AA 20-258)

N° du produit ABIN4950633

Cet anticorps Lapin Polyclonal détecte spécifiquement Ceruloplasmin dans WB et IHC (p). Il présente une réactivité avec des échantillons de Rat et Souris.

Aperçu rapide pour Ceruloplasmin anticorps (AA 20-258) (ABIN4950633)

Antigène: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ceruloplasmin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Ceruloplasmin anticorps

Épitope: AA 20-258

Purification: Antigen affinity

Immunogène: Amino acids 20-258 of mouse Ceruloplasmin were used as the immunogen for the CP antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CP antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Ceruloplasmin

Antigène: Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))

Autre désignation: Ceruloplasmin / CP

Sujet: Ceruloplasmin (or Caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene. It is mapped to 3q23-q25. The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

UniProt: Q61147

Pathways: Transition Metal Ion Homeostasis