NKX3-1 anticorps (AA 118-145)

N° du produit ABIN3032013

Cet anticorps anti-NKX3-1 est un anticorps Lapin Polyclonal détectant NKX3-1 dans WB, IHC, ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour NKX3-1 anticorps (AA 118-145) (ABIN3032013)

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKX3-1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Détail du produit anti-NKX3-1 anticorps

Épitope: AA 118-145

Réactivité croisée (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 118-145 from the human protein was used as the immunogen for this NKX3.1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the NKX3.1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4°C for up to one month. For long term, aliquot the NKX3.1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur NKX3-1

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Autre désignation: NKX3.1

Sujet: NKX3.1 is a transcription factor which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. [UniProt]

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus