Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ACE2 anticorps (AA 59-90)

ACE2 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3029962
  • Antigène Voir toutes ACE2 Anticorps
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    Épitope
    • 16
    • 16
    • 14
    • 10
    • 9
    • 9
    • 8
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 59-90
    Reactivité
    • 149
    • 54
    • 47
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 136
    • 20
    • 6
    Lapin
    Clonalité
    • 116
    • 46
    Polyclonal
    Conjugué
    • 79
    • 18
    • 12
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ACE2 est non-conjugé
    Application
    • 129
    • 75
    • 56
    • 36
    • 36
    • 19
    • 17
    • 11
    • 11
    • 10
    • 10
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Purified
    Immunogène
    A portion of amino acids 59-90 from the human protein was used as the immunogen for this ACE2 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ACE2 Anticorps primaire
  • Indications d'application
    Titration of the ACE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot the ACE2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Antigène
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    Autre désignation
    ACE2 (ACE2 Produits)
    Synonymes
    anticorps ACE1, anticorps CD143, anticorps DCP, anticorps DCP1, anticorps ICH, anticorps MVCD3, anticorps ACEH, anticorps 2010305L05Rik, anticorps zgc:92514, anticorps angiotensin I converting enzyme, anticorps angiotensin I converting enzyme 2, anticorps angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, anticorps ACE, anticorps ACE2, anticorps Ace2, anticorps ace2
    Sujet
    This gene encodes a deduced 805-amino acid protein containing a potential 17-amino acid N-terminal signal peptide and a putative 22-amino acid C-terminal membrane anchor. It also possesses a zinc metalloprotease consensus sequence and a conserved glutamine residue that may function as a third zinc ligand. ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel constrictor, while angiotensin 1-9 does not impact blood vessels but is cleaved by ACE to a shorter peptide, angiotensin 1-7, which is a blood vessel dilator. Spike (S) proteins of coronaviruses, including the SARS coronavirus, bind with cellular receptors to mediate infection of target cells. ACE-2 binds the S1 domain of the SARS coronavirus S protein. SARS coronavirus replicates efficiently on ACE2-transfected but not mock-transfected 293T cells. Anti-ACE-2 but not anti-ACE1 antibody blocks viral replication on Vero E6 cells. It has been proposed that ACE2 is a functional receptor for SARS coronavirus.
    UniProt
    Q9BYF1
    Pathways
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
Vous êtes ici:
Support technique