ALPL anticorps (AA 217-246)

N° du produit ABIN3029909

L’anticorps Lapin Polyclonal anti-ALPL a été validé pour WB, ELISA, IHC, FACS et IF. Il convient pour détecter ALPL dans des échantillons de Humain et Souris.

Aperçu rapide pour ALPL anticorps (AA 217-246) (ABIN3029909)

Antigène: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALPL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-ALPL anticorps

Épitope: AA 217-246

Purification: Purified

Immunogène: A portion of amino acids 217-246 from human ALPL was used as the immunogen for this Alkaline Phosphatase antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Alkaline Phosphatase antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Alkaline Phosphatase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur ALPL

Antigène: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Autre désignation: Alkaline Phosphatase (liver)

Sujet: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The genes for the first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. This protein is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.

UniProt: P05186