AMACR anticorps (AA 323-351)
Aperçu rapide pour AMACR anticorps (AA 323-351) (ABIN3029920)
Antigène
Voir toutes AMACR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 323-351
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Fonction
- AMACR Antibody
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 323-351 from the human protein was used as the immunogen for this AMACR antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the AMACR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the AMACR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Autre désignation
- AMACR
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Sujet
- This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
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UniProt
- Q9UHK6
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Pathways
- Monocarboxylic Acid Catabolic Process
Antigène
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