ANGPTL4 anticorps (AA 138-167)
Aperçu rapide pour ANGPTL4 anticorps (AA 138-167) (ABIN3029955)
Antigène
Voir toutes ANGPTL4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 138-167
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Fonction
- ANGPTL4 Antibody
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Purification
- Purified
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Immunogène
- A portion of amino acids 138-167 from the human protein was used as the immunogen for this ANGPTL4 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the ANGPTL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Aliquot the ANGPTL4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
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Autre désignation
- ANGPTL4
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Sujet
- ANGPTL4 is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This protein is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. The encoded protein is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. The encoded protein may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes.
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UniProt
- Q9BY76
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Antigène
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