Androgen Receptor anticorps (AA 475-504)

N° du produit ABIN3029943

Cet anticorps anti-Androgen Receptor Polyclonal Lapin (ABIN3029943) détecte spécifiquement Androgen Receptor dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Androgen Receptor anticorps (AA 475-504) (ABIN3029943)

Antigène: Androgen Receptor (AR)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Androgen Receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Androgen Receptor anticorps

Épitope: AA 475-504

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 475-504 from the human protein was used as the immunogen for this AR antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the AR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the AR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Androgen Receptor

Antigène: Androgen Receptor (AR)

Autre désignation: AR

Sujet: The androgen receptor, also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding either of the androgenic hormones, testosterone, or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. It is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor.
The main function of the AR is as a DNA-binding transcription factor that regulates gene expression, however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype. [Wiki]

UniProt: P10275

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding