ASCL1 anticorps (AA 63-90)

N° du produit ABIN3029829

Cet anticorps anti-ASCL1 est un anticorps Lapin Polyclonal détectant ASCL1 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour ASCL1 anticorps (AA 63-90) (ABIN3029829)

Antigène: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASCL1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ASCL1 anticorps

Épitope: AA 63-90

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 63-90 from the human protein was used as the immunogen for this MASH1 / ASCL1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the ASCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ASCL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur ASCL1

Antigène: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Autre désignation: ASCL1 (MASH1)

Sujet: This gene encodes 'Achaete scute complex homolog like 1' (ASCL1) or 'Mammalian achaete scute complex homolog 1' (MASH1), a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.

UniProt: P50553

Pathways: Dopaminergic Neurogenesis