ATG12 anticorps (AA 1-50)

N° du produit ABIN3030084

Cet anticorps anti-ATG12 est un anticorps Lapin Polyclonal détectant ATG12 dans WB, ELISA et IF. Adapté pour Humain et Souris.

Aperçu rapide pour ATG12 anticorps (AA 1-50) (ABIN3030084)

Antigène: ATG12 (Autophagy Related 12 (ATG12))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG12 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-ATG12 anticorps

Épitope: AA 1-50

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 1-50 from the human protein was used as the immunogen for this ATG12 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the ATG12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ATG12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur ATG12

Antigène: ATG12 (Autophagy Related 12 (ATG12))

Autre désignation: ATG12

Sujet: Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).

APG12L/ATG12 is the human homolog of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy.

UniProt: O94817

Pathways: Autophagy