BNIP3 anticorps (AA 152-187)

N° du produit ABIN3030151

Cet anticorps Lapin Polyclonal détecte spécifiquement BNIP3 dans WB, IHC, ELISA et IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour BNIP3 anticorps (AA 152-187) (ABIN3030151)

Antigène: BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BNIP3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-BNIP3 anticorps

Épitope: AA 152-187

Purification: Purified

Immunogène: A portion of amino acids 152-187 from the human protein (BH3 domain) was used as the immunogen for this BNIP3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the BNIP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:50-1:100,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the BNIP3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur BNIP3

Antigène: BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

Autre désignation: BNIP3

Sujet: NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.

UniProt: Q12983

Pathways: Autophagy, Brown Fat Cell Differentiation