CCR1 anticorps (AA 1-30)

N° du produit ABIN3030216

Détail du produit anti-CCR1 anticorps

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Épitope: AA 1-30

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR1 est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 1-30 from the human protein was used as the immunogen for this CCR1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the CCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CCR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur CCR1

Antigène: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Autre désignation: CCR1 (CCR1 Produits)

Synonymes: anticorps CD191, anticorps CKR-1, anticorps CKR1, anticorps CMKBR1, anticorps HM145, anticorps MIP1aR, anticorps SCYAR1, anticorps Cmkbr1, anticorps Mip-1a-R, anticorps C-C motif chemokine receptor 1, anticorps chemokine (C-C motif) receptor 1, anticorps CCR1, anticorps Ccr1

Sujet: CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.

UniProt: P32246