CD46 anticorps (AA 330-361)

N° du produit ABIN3030406

Cet anticorps Lapin Polyclonal détecte spécifiquement CD46 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour CD46 anticorps (AA 330-361) (ABIN3030406)

Antigène: CD46

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD46 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CD46 anticorps

Épitope: AA 330-361

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 330-361 from the human protein was used as the immunogen for this CD46 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the CD46 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CD46 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur CD46

Antigène: CD46

Autre désignation: CD46

Sujet: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization