CDC6 anticorps (AA 32-61)
Aperçu rapide pour CDC6 anticorps (AA 32-61) (ABIN3030464)
Antigène
Voir toutes CDC6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 32-61
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 32-61 from the human protein was used as the immunogen for this CDC6 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the CDC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the CDC6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
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Autre désignation
- CDC6
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Sujet
- Human CDC6 is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
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UniProt
- Q99741
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Pathways
- DNA Replication, Synthesis of DNA
Antigène
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