Claudin 2 anticorps (AA 135-164)

N° du produit ABIN3030535

Détail du produit anti-Claudin 2 anticorps

Antigène: Claudin 2 (CLDN2)

Épitope: AA 135-164

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée (Details): Expected species reactivity: Mouse, Bovine

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 135-164 from the human protein was used as the immunogen for this Claudin 2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Claudin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Claudin 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Claudin 2

Antigène: Claudin 2 (CLDN2)

Abstract: CLDN2 Produits

Synonymes: anticorps CLDN2, anticorps zgc:92260, anticorps AL022813, anticorps RGD1560247, anticorps claudin 2, anticorps CLDN2, anticorps cldn2, anticorps Cldn2

Sujet: Claudin-2 is expressed in cation-leaky epithelia such as that of the kidney proximal tubule. Mice that are deficient in the protein have reduced reabsorption of Na+ in the proximal tubule, consistent with a role in paracellular transport. Similar results have been obtained with cultured cells, as overexpression in CLDN2 lacking cells leads to increase of permeability for small cations. Furthermore, CLDN2 has been shown to form paracellular channels for water. [Wiki]

UniProt: P57739

Pathways: Hepatitis C