CPT1C anticorps (AA 752-782)

N° du produit ABIN3030283

Cet anticorps Lapin Polyclonal détecte spécifiquement CPT1C dans WB, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CPT1C anticorps (AA 752-782) (ABIN3030283)

Antigène: CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPT1C est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-CPT1C anticorps

Épitope: AA 752-782

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 752-782 from the human protein was used as the immunogen for this CPT1C antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the CPT1C antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the CPT1C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur CPT1C

Antigène: CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

Autre désignation: CPT1C

Sujet: The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.

UniProt: Q8TCG5

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process