CUX1 anticorps (AA 1347-1374)
Aperçu rapide pour CUX1 anticorps (AA 1347-1374) (ABIN3030580)
Antigène
Voir toutes CUX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1347-1374
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Fonction
- CUX1 Antibody / Homeobox protein cut-like 1
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 1347-1374 from the human protein was used as the immunogen for this CUX1 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the CUX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the CUX1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CUX1 (Cut-Like Homeobox 1 (CUX1))
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Autre désignation
- CUX1
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Sujet
- CUX1 likely has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor, binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer, may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity). [UniProt]
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UniProt
- P39880
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Pathways
- Cellular Glucan Metabolic Process
Antigène
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