DCLK2 anticorps (AA 167-196)

N° du produit ABIN3030772

Cet anticorps Lapin Polyclonal détecte spécifiquement DCLK2 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour DCLK2 anticorps (AA 167-196) (ABIN3030772)

Antigène: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCLK2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DCLK2 anticorps

Épitope: AA 167-196

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 167-196 from the human protein was used as the immunogen for this DCLK2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the DCLK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the DCLK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur DCLK2

Antigène: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Autre désignation: DCLK2

Sujet: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.

UniProt: Q8N568