RCAN1 anticorps (AA 222-252)

N° du produit ABIN3032453

L’anticorps Lapin Polyclonal anti-RCAN1 a été validé pour WB et ELISA. Il convient pour détecter RCAN1 dans des échantillons de Humain.

Aperçu rapide pour RCAN1 anticorps (AA 222-252) (ABIN3032453)

Antigène: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RCAN1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RCAN1 anticorps

Épitope: AA 222-252

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat, Bovine, Hamster

Purification: Purified

Immunogène: A portion of amino acids 222-252 from the human protein was used as the immunogen for this DSCR1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the DSCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the DSCR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur RCAN1

Antigène: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Autre désignation: DSCR1

Sujet: DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.

UniProt: P53805

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development