GAK anticorps (AA 15-45)

N° du produit ABIN3030600

Cet anticorps anti-GAK est un anticorps Lapin Polyclonal détectant GAK dans WB, ELISA et IHC. Adapté pour Humain et Souris.

Aperçu rapide pour GAK anticorps (AA 15-45) (ABIN3030600)

Antigène: GAK (Cyclin G Associated Kinase (GAK))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-GAK anticorps

Épitope: AA 15-45

Réactivité croisée (Details): Expected species reactivity: Rat

Purification: Purified

Immunogène: A portion of amino acids 15-45 from the human protein was used as the immunogen for this GAK antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the GAK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100,Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the GAK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur GAK

Antigène: GAK (Cyclin G Associated Kinase (GAK))

Autre désignation: GAK

Sujet: GAK, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5. It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK localizes to the perinuclear area and to the trans-Golgi network. It is also observed on the plasma membrane, probably at focals adhesions. Expression is ubiquitous, wiht highest levels in testis. The protein contains 1 J domain and 1 tensin domain.

UniProt: Q6P490