HOPX anticorps (AA 22-54)
Aperçu rapide pour HOPX anticorps (AA 22-54) (ABIN3031254)
Antigène
Voir toutes HOPX AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 22-54
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Purification
- Antigen affinity purified
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Immunogène
- This mouse Hopx antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 22-54 amino acids from the Central region of mouse Hopx.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the Hopx antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Hopx antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- HOPX (HOP Homeobox (HOPX))
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Autre désignation
- Hopx
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Sujet
- Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy.
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UniProt
- Q8R1H0
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Pathways
- Regulation of Muscle Cell Differentiation
Antigène
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