IRF4 anticorps (AA 164-191)

N° du produit ABIN3031420

Cet anticorps Lapin Polyclonal détecte spécifiquement IRF4 dans WB, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour IRF4 anticorps (AA 164-191) (ABIN3031420)

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF4 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-IRF4 anticorps

Épitope: AA 164-191

Purification: Purified

Immunogène: A portion of amino acids 164-191 from the human protein was used as the immunogen for this IRF4 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the IRF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the IRF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur IRF4

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Autre désignation: IRF4

Sujet: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

UniProt: Q15306

Pathways: Chromatin Binding