MECP2 anticorps (AA 58-87)

N° du produit ABIN3031763

L’anticorps anti-MECP2 Polyclonal Lapin est utilisé pour la détection de MECP2 dans des échantillons de Humain. Il a été validé pour WB, IHC, ELISA et FACS.

Aperçu rapide pour MECP2 anticorps (AA 58-87) (ABIN3031763)

Antigène: MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MECP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Détail du produit anti-MECP2 anticorps

Épitope: AA 58-87

Fonction: MeCP2 Antibody

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat, Primate

Purification: Antigen affinity

Immunogène: A portion of amino acids 58-87 from the human protein was used as the immunogen for this MeCP2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the MeCP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MeCP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MECP2

Antigène: MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Autre désignation: MeCP2

Sujet: MeCP2 is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). [UniProt]

UniProt: P51608

Pathways: Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane