MUC1 anticorps (AA 1176-1205)

N° du produit ABIN3031859

L’anticorps Lapin Polyclonal anti-MUC1 a été validé pour IHC, WB et ELISA. Il convient pour détecter MUC1 dans des échantillons de Humain.

Aperçu rapide pour MUC1 anticorps (AA 1176-1205) (ABIN3031859)

Antigène: MUC1 (Mucin 1 (MUC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUC1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Détail du produit anti-MUC1 anticorps

Épitope: AA 1176-1205

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 1176-1205 from the human protein was used as the immunogen for this MUC-1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the MUC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MUC-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur MUC1

Antigène: MUC1 (Mucin 1 (MUC1))

Autre désignation: MUC-1

Sujet: This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq].

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling