NEUROD1 anticorps (AA 318-348)

N° du produit ABIN3031978

Détail du produit anti-NEUROD1 anticorps

Antigène: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Épitope: AA 318-348

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEUROD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Purified

Immunogène: A portion of amino acids 318-348 from the human protein was used as the immunogen for this NeuroD1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the NeuroD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the NeuroD1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur NEUROD1

Antigène: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Autre désignation: NeuroD1 (NEUROD1 Produits)

Synonymes: anticorps BETA2, anticorps BHF-1, anticorps MODY6, anticorps NEUROD, anticorps bHLHa3, anticorps Neurod, anticorps neurod, anticorps XNeuroD, anticorps MGC82572, anticorps NEUROD1, anticorps ND1, anticorps beta2, anticorps bhf-1, anticorps neuro-D, anticorps nrd, anticorps neuroD, anticorps neurod1, anticorps Beta2, anticorps neuronal differentiation 1, anticorps neurogenic differentiation 1, anticorps neuronal differentiation 1 S homeolog, anticorps neuronal differentiation 1 L homeolog, anticorps NEUROD1, anticorps Neurod1, anticorps neurod1.S, anticorps neurod1, anticorps neurod1.L

Sujet: NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis