NEUROD1 anticorps (AA 318-348)

N° du produit ABIN3031978

Cet anticorps Lapin Polyclonal détecte spécifiquement NEUROD1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NEUROD1 anticorps (AA 318-348) (ABIN3031978)

Antigène: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEUROD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NEUROD1 anticorps

Épitope: AA 318-348

Fonction: NeuroD1 Antibody

Purification: Purified

Immunogène: A portion of amino acids 318-348 from the human protein was used as the immunogen for this NeuroD1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the NeuroD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the NeuroD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur NEUROD1

Antigène: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Autre désignation: NeuroD1

Sujet: NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis