NKX3-1 anticorps (AA 3-1)

N° du produit ABIN3032012

L’anticorps anti-NKX3-1 Polyclonal Lapin est utilisé pour la détection de NKX3-1 dans des échantillons de Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour NKX3-1 anticorps (AA 3-1) (ABIN3032012)

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKX3-1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NKX3-1 anticorps

Épitope: AA 3-1

Fonction: Nkx3.1 Antibody

Purification: Antigen affinity

Immunogène: A portion of amino acids 3-1 from the mouse protein was used as the immunogen for this Nkx3.1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Nkx3.1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Nkx3.1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur NKX3-1

Antigène: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Autre désignation: Nkx3.1

Sujet: Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity). Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells. Play a role in the formation of minor salivary glands (particularly palatine and lingual glands). Essential for appropriate differentiation and secretory function of the bulbourethral gland.

UniProt: P97436

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus