NUP50 anticorps (AA 432-461)

N° du produit ABIN3032078

L’anticorps anti-NUP50 Polyclonal Lapin est utilisé pour la détection de NUP50 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour NUP50 anticorps (AA 432-461) (ABIN3032078)

Antigène: NUP50 (Nucleoporin 50kDa (NUP50))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUP50 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NUP50 anticorps

Épitope: AA 432-461

Fonction: NUP50 Antibody

Réactivité croisée (Details): Expected species reactivity: Rat

Purification: Purified

Immunogène: A portion of amino acids 432-461 from the human protein was used as the immunogen for this NUP50 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the NUP50 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the NUP50 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur NUP50

Antigène: NUP50 (Nucleoporin 50kDa (NUP50))

Autre désignation: NUP50

Sujet: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.

UniProt: Q9UKX7

Pathways: Tube Formation