NUP50 anticorps (AA 432-461)

N° du produit ABIN3032078

Détail du produit anti-NUP50 anticorps

Antigène: NUP50 (Nucleoporin 50kDa (NUP50))

Épitope: AA 432-461

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUP50 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): Expected species reactivity: Rat

Purification: Purified

Immunogène: A portion of amino acids 432-461 from the human protein was used as the immunogen for this NUP50 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the NUP50 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the NUP50 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur NUP50

Antigène: NUP50 (Nucleoporin 50kDa (NUP50))

Autre désignation: NUP50 (NUP50 Produits)

Synonymes: anticorps wu:fa56e03, anticorps wu:fb78a08, anticorps GB18194, anticorps npap60, anticorps npap60l, anticorps Nup50, anticorps Rtp60, anticorps 1700030K07Rik, anticorps AI413123, anticorps Npap60, anticorps NPAP60, anticorps NPAP60L, anticorps nucleoporin 50, anticorps nuclear pore complex protein Nup50, anticorps nucleoporin 50kDa S homeolog, anticorps nucleoporin 50kDa, anticorps nup50, anticorps LOC410864, anticorps NUP50, anticorps nup50.S, anticorps CpipJ_CPIJ012737, anticorps Nup50

Sujet: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP50 is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. It interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.

UniProt: Q9UKX7

Pathways: Tube Formation