P-Glycoprotein anticorps (AA 647-677)

N° du produit ABIN3032111

L’anticorps Lapin Polyclonal anti-P-Glycoprotein a été validé pour WB et ELISA. Il convient pour détecter P-Glycoprotein dans des échantillons de Humain.

Aperçu rapide pour P-Glycoprotein anticorps (AA 647-677) (ABIN3032111)

Antigène: P-Glycoprotein

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P-Glycoprotein est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-P-Glycoprotein anticorps

Épitope: AA 647-677

Purification: Purified

Immunogène: A portion of amino acids 647-677 from the human protein was used as the immunogen for this P-Glycoprotein antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the P-Glycoprotein antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the P-Glycoprotein antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur P-Glycoprotein

Antigène: P-Glycoprotein

Sujet: The membrane-associated ABCB1 protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. ABCB1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

UniProt: P08183