Tumor Protein p73 anticorps (AA 288-317)
Aperçu rapide pour Tumor Protein p73 anticorps (AA 288-317) (ABIN3029400)
Antigène
Voir toutes Tumor Protein p73 (TP73) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 288-317
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Fonction
- p73 Antibody
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 288-317 from the human protein was used as the immunogen for this p73 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the p73 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the p73 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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Autre désignation
- p73
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Sujet
- TP73 is tumor protein p73, which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73 and have high sequence similarity to one another, which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways involving direct or indirect protein interactions, resulting in regulation of the same target gene promoters or regulation of each other's promoters. The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors.
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UniProt
- O15350
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Pathways
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
Antigène
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