MUC1 anticorps (pThr1224)

N° du produit ABIN3031864

Cet anticorps Lapin Polyclonal détecte spécifiquement MUC1 dans ELISA, IF et DB. Il présente une réactivité envers Humain.

Aperçu rapide pour MUC1 anticorps (pThr1224) (ABIN3031864)

Antigène: MUC1 (Mucin 1 (MUC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUC1 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Dot Blot (DB)

Détail du produit anti-MUC1 anticorps

Épitope: pThr1224

Purification: Antigen affinity purified

Immunogène: This phospho-MUC1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT1224 of human MUC1.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the phospho-MUC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500,Immunofluorescence: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the phospho-MUC1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur MUC1

Antigène: MUC1 (Mucin 1 (MUC1))

Autre désignation: MUC1

Sujet: MUC1 is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling