OCT4 anticorps (pSer236)

N° du produit ABIN3032291

L’anticorps Lapin Polyclonal anti-OCT4 a été validé pour ELISA et DB. Il convient pour détecter OCT4 dans des échantillons de Humain.

Aperçu rapide pour OCT4 anticorps (pSer236) (ABIN3032291)

Antigène: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OCT4 est non-conjugé

Application: ELISA, Dot Blot (DB)

Détail du produit anti-OCT4 anticorps

Épitope: pSer236

Réactivité croisée (Details): Expected species reactivity: Mouse, Bovine, Pig

Purification: Antigen affinity purified

Immunogène: This phospho-Oct4 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS236 of human OCT4.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the phospho-Oct4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the phospho-Oct4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur OCT4

Antigène: OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))

Autre désignation: Oct4

Sujet: OCT4 encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6,22)(p21,q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

UniProt: Q01860

Pathways: Stem Cell Maintenance