PRKD3 anticorps (AA 860-890)
Aperçu rapide pour PRKD3 anticorps (AA 860-890) (ABIN3032381)
Antigène
Voir toutes PRKD3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 860-890
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Fonction
- PKC nu Antibody
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Réactivité croisée (Details)
- Expected species reactivity: Mouse
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Purification
- Purified
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Immunogène
- A portion of amino acids 860-890 from the human protein was used as the immunogen for this PKC nu antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the PKC nu antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the PKC nu antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PRKD3 (Protein Kinase D3 (PRKD3))
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Autre désignation
- PKC nu
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Sujet
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.
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UniProt
- O94806
Antigène
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