PRDM2 anticorps (AA 1-347)

N° du produit ABIN3032300

L’anticorps anti-PRDM2 Monoclonal Souris est utilisé pour la détection de PRDM2 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA et ChIP.

Aperçu rapide pour PRDM2 anticorps (AA 1-347) (ABIN3032300)

Antigène: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRDM2 est non-conjugé

Application: Western Blotting (WB), ELISA, Chromatin Immunoprecipitation (ChIP)

Clone: 33AT1045

Détail du produit anti-PRDM2 anticorps

Épitope: AA 1-347

Fonction: RIZ1 Antibody

Purification: Purified

Immunogène: Purified recombinant GST fusion protein encoding aa 1-347 of human RIZ1. This RIZ1 antibody is specific and does not recognize the beta isoform (RIZ2).

Isotype: IgG1

Information d'application

Indications d'application: Titration of the RIZ1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the RIZ1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PRDM2

Antigène: PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Autre désignation: RIZ1

Sujet: This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q13029