RPS6 anticorps (AA 220-249)
Aperçu rapide pour RPS6 anticorps (AA 220-249) (ABIN3032477)
Antigène
Voir toutes RPS6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 220-249
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Réactivité croisée (Details)
- Expected species reactivity: Mouse, Rat, Bovine, Primate, Chicken, Xenopus
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Purification
- Antigen affinity purified
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Immunogène
- A portion of amino acids 220-249 from the human protein was used as the immunogen for this RPS6 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the RPS6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the RPS6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- RPS6 (Ribosomal Protein S6 (RPS6))
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Autre désignation
- RPS6
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Sujet
- Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
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UniProt
- P62753
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Pathways
- Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Antigène
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