SOX17 anticorps (C-Term)

N° du produit ABIN3032723

L’anticorps anti-SOX17 Polyclonal Lapin est utilisé pour la détection de SOX17 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour SOX17 anticorps (C-Term) (ABIN3032723)

Antigène: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX17 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SOX17 anticorps

Épitope: AA 376-409, C-Term

Fonction: Sox17 Antibody

Purification: Antigen affinity

Immunogène: This Sox17 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of mouse Sox17.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Sox17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Sox17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SOX17

Antigène: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Autre désignation: Sox17

Sujet: Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.

UniProt: Q61473