SOX17 anticorps (C-Term)

N° du produit ABIN3032723

Détail du produit anti-SOX17 anticorps

Antigène: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX17 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antigen affinity purified

Immunogène: This Sox17 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of mouse Sox17.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Sox17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Sox17 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur SOX17

Antigène: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Autre désignation: Sox17 (SOX17 Produits)

Synonymes: anticorps VUR3, anticorps SOX17, anticorps Sox17alpha, anticorps Xsox17, anticorps Xsox17-alpha, anticorps Xsox17alpha, anticorps sox17-alpha, anticorps tSox17alpha, anticorps xSox17alpha1, anticorps xSox17alpha2, anticorps xsox17a, anticorps sox17, anticorps sox7/17, anticorps Sox, anticorps SRY-box 17, anticorps SRY (sex determining region Y)-box 17, anticorps SRY box 17, anticorps SRY-box 17 alpha, anticorps sox7/17 protein, anticorps SOX17, anticorps sox17, anticorps Sox17, anticorps sox17a, anticorps sox7/17

Sujet: Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.

UniProt: Q61473