SOX7 anticorps (C-Term)

N° du produit ABIN3032740

Détail du produit anti-SOX7 anticorps

Antigène: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOX7 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogène: This SOX7 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 319-353 amino acids from the C-terminal region of human SOX7.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the SOX7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SOX7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur SOX7

Antigène: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Autre désignation: SOX7 (SOX7 Produits)

Synonymes: anticorps sox7-A, anticorps xSox7, anticorps SRY-box 7, anticorps SRY (sex determining region Y)-box 7, anticorps SRY box 7, anticorps SRY-box 7 L homeolog, anticorps SOX7, anticorps Sox7, anticorps sox7, anticorps sox7.L

Sujet: Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.

UniProt: Q9BT81

Pathways: Positive Regulation of Endopeptidase Activity