SUMO2 anticorps

N° du produit ABIN3032647

Cet anticorps Souris Monoclonal détecte spécifiquement SUMO2 dans WB, ELISA et IF. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour SUMO2 anticorps (ABIN3032647)

Antigène: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SUMO2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 973CT8-1-1

Détail du produit anti-SUMO2 anticorps

Réactivité croisée (Details): Expected species reactivity: Bovine, Chicken, Hamster, Mouse, Pig, Primate

Purification: Purified

Immunogène: Purified His-tagged protein was used to produced this monoclonal SUMO-2 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Titration of the SUMO-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25,Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SUMO-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur SUMO2

Antigène: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Autre désignation: SUMO-2

Sujet: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.

UniProt: P61956

Pathways: Methionine Biosynthetic Process