SUZ12 anticorps (AA 496-530)
Aperçu rapide pour SUZ12 anticorps (AA 496-530) (ABIN3029057)
Antigène
Voir toutes SUZ12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 496-530
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Fonction
- Suz12 Antibody
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Réactivité croisée (Details)
- Expected species reactivity: Human
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Purification
- Antigen affinity
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Immunogène
- This Suz12 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 496-530 amino acids from the mouse protein.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the Suz12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Suz12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))
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Autre désignation
- Suz12
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Sujet
- Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems (By similarity). Genes repressed by the PRC2/EED-EZH2 complex include HOXA7, HOXB6 and HOXC8.
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UniProt
- Q80U70
Antigène
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